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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1549988
Species: Mus musculus
RGD Object: Gene
Symbol: Tlr9
Name: toll-like receptor 9
Acc ID: CHEBI:15379
Term: dioxygen
Definition: An elemental molecule that has formula O2.
Chemical ID: MESH:D010100
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Tlr9increases expressionISOTLR9 (Homo sapiens)6480464CTDOxygen deficiency results in increased expression of TLR9 mRNAPMID:24273604
Tlr9multiple interactionsISOTLR9 (Homo sapiens)6480464CTDChloroquine inhibits the reaction [Oxygen deficiency results in increased expression of TLR9 mRNA]; Oxygen deficiency inhibits the reaction [Chloroquine results in increased expression of TLR9 mRNA]; TLR9 protein promotes the reaction [Oxygen deficiency promotes the reaction [Chloroquine results in increased expression of MMP13 mRNA]]PMID:24273604
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