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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1311417
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Col7a1
Name: collagen type VII alpha 1 chain
Acc ID: CHEBI:15379
Term: dioxygen
Definition: An elemental molecule that has formula O2.
Chemical ID: MESH:D010100
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
QualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
increases expressionISORGD:13228696480464CTDOxygen deficiency results in increased expression of COL7A1 mRNA, Oxygen deficiency results in increased expression of COL7A1 protein

PMID:30381462
multiple interactionsISORGD:13228696480464CTDHIF1A protein promotes the reaction [Oxygen deficiency results in increased expression of COL7A1 mRNA], SMARCA2 protein promotes the reaction [Oxygen deficiency results in increased expression of COL7A1 mRNA], SMARCA4 protein promotes the reaction [Oxygen deficiency results in increased expression of COL7A1 mRNA], TP53 protein mutant form promotes the reaction [Oxygen deficiency results in increased expression of COL7A1 mRNA], TP53 protein mutant form promotes the reaction [Oxygen deficiency results in increased expression of COL7A1 protein]

PMID:30381462
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.