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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1307773
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Pgp
Name: phosphoglycolate phosphatase
Acc ID: CHEBI:15379
Term: dioxygen
Definition: An elemental molecule that has formula O2.
Chemical ID: MESH:D010100
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
QualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
affects methylationISORGD:13320046480464CTDOxygen deficiency affects the methylation of PGP promoter

PMID:24205000
decreases expressionISORGD:13510966480464CTDOxygen deficiency results in decreased expression of PGP mRNA

PMID:26516004
increases expressionISORGD:13320046480464CTDOxygen deficiency results in increased expression of PGP mRNA

PMID:20880076, PMID:24205000
multiple interactionsISORGD:13320046480464CTD[sulforafan affects the susceptibility to Oxygen] which affects the expression of PGP mRNA

PMID:30529165
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.