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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1306612
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Car12
Name: carbonic anhydrase 12
Acc ID: CHEBI:15379
Term: dioxygen
Definition: An elemental molecule that has formula O2.
Chemical ID: MESH:D010100
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Car12multiple interactionsEXP 6480464CTD[Oxygen deficiency co-treated with Blood Glucose deficiency co-treated with Particulate Matter] results in increased expression of CAR12 mRNAPMID:33729688
Car12increases expressionISOCA12 (Homo sapiens)6480464CTDOxygen deficiency results in increased expression of CA12 mRNA; Oxygen deficiency results in increased expression of CA12 proteinPMID:19695866 PMID:20042640 PMID:21851094
Car12multiple interactionsISOCA12 (Homo sapiens)6480464CTD[4-(4-((2',3',4',6'-tetra-O-acetylglucopyranosyl)thiomethyl)-5-iodo-1-H-1,2,3-triazol-1-yl)benzenesulfonamide inhibits the reaction [Oxygen deficiency results in increased expression of CA9 protein]] which results in increased expression of CA12 proteinPMID:21851094
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