GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | Mdm2 | increases expression | ISO | MDM2 (Homo sapiens) | 6480464 | CTD | Oxygen deficiency results in increased expression of MDM2 mRNA; Oxygen deficiency results in increased expression of MDM2 protein | PMID:19502547 PMID:19578757 PMID:19714248 PMID:25596134 | Mdm2 | multiple interactions | ISO | MDM2 (Homo sapiens) | 6480464 | CTD | [Cisplatin co-treated with eprenetapopt co-treated with Oxygen deficiency] results in increased expression of MDM2 mRNA; [Oxygen deficiency co-treated with eprenetapopt] results in increased expression of MDM2 mRNA; alpha-naphthoflavone inhibits the reaction [Tetrachlorodibenzodioxin promotes the reaction [Oxygen deficiency results in increased expression of MDM2 mRNA]]; Tetrachlorodibenzodioxin promotes the reaction [Oxygen deficiency results in increased expression of MDM2 mRNA]; Tetrachlorodibenzodioxin promotes the reaction [Oxygen deficiency results in increased expression of MDM2 protein] | PMID:19578757 PMID:29690507 | Mdm2 | multiple interactions | ISO | Mdm2 (Mus musculus) | 6480464 | CTD | [NFE2L2 protein affects the susceptibility to Oxygen] which affects the expression of MDM2 mRNA | PMID:30529165 | | ||||||||||||||||||||||
| Go Back to source page | Continue to Ontology report |