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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 10216
Species: Homo sapiens
RGD Object: Gene
Symbol: ATP7A
Name: ATPase copper transporting alpha
Acc ID: CHEBI:15379
Term: dioxygen
Definition: An elemental molecule that has formula O2.
Chemical ID: MESH:D010100
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
ATP7Aincreases expressionEXP 6480464CTDOxygen deficiency results in increased expression of ATP7A mRNAPMID:24614111
ATP7Aaffects localizationISOAtp7a (Mus musculus)6480464CTDOxygen deficiency affects the localization of ATP7A proteinPMID:19351718
ATP7Aincreases expressionISOAtp7a (Mus musculus)6480464CTDOxygen deficiency results in increased expression of ATP7A mRNA; Oxygen deficiency results in increased expression of ATP7A proteinPMID:19351718 PMID:24614111
ATP7Amultiple interactionsISOAtp7a (Mus musculus)6480464CTDtetrathiomolybdate inhibits the reaction [Oxygen deficiency affects the localization of ATP7A protein]PMID:19351718
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