GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | EPO | multiple interactions | EXP | | 6480464 | CTD | EPO protein inhibits the reaction [GCH1 mutant form results in decreased abundance of sapropterin] | PMID:25041251 | EPO | increases abundance | ISO | Epo (Mus musculus) | 6480464 | CTD | EPO protein results in increased abundance of sapropterin | PMID:25490417 | EPO | multiple interactions | ISO | Epo (Mus musculus) | 6480464 | CTD | EPO protein inhibits the reaction [[GCH1 gene mutant form results in increased oxidation of sapropterin] which results in increased chemical synthesis of 7,8-dihydrobiopterin]; EPO protein inhibits the reaction [[NOS3 protein co-treated with sapropterin deficiency] results in increased chemical synthesis of Superoxides]; EPO protein inhibits the reaction [HPH1 gene mutant form results in increased oxidation of sapropterin] | PMID:25041251 PMID:25490417 | | ||||||||||||||||||||||
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