GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | Keap1 | increases expression | ISO | Keap1 (Mus musculus) | 6480464 | CTD | Acrolein results in increased expression of KEAP1 protein | PMID:30608172 | Keap1 | multiple interactions | ISO | KEAP1 (Homo sapiens) | 6480464 | CTD | [KEAP1 gene mutant form results in increased activity of NFE2L2] which results in decreased susceptibility to Acrolein; Buthionine Sulfoximine inhibits the reaction [[KEAP1 gene mutant form results in increased activity of NFE2L2] which results in decreased susceptibility to Acrolein] | PMID:19608619 | Keap1 | multiple interactions | ISO | Keap1 (Mus musculus) | 6480464 | CTD | [Ovalbumin co-treated with Acrolein] results in increased expression of KEAP1 protein | PMID:30608172 | | ||||||||||||||||||||||
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