GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | IL6 | increases expression | EXP | | 6480464 | CTD | Acrolein results in increased expression of IL6 mRNA; Acrolein results in increased expression of IL6 protein | PMID:36055550 | IL6 | increases secretion | EXP | | 6480464 | CTD | Acrolein results in increased secretion of IL6 protein | PMID:30204913 | IL6 | multiple interactions | EXP | | 6480464 | CTD | [Acrolein co-treated with Formaldehyde co-treated with Ozone] results in increased expression of IL6 protein; Acetylcysteine inhibits the reaction [Acrolein promotes the reaction [Lipopolysaccharides results in increased expression of IL6 mRNA]]; Acetylcysteine inhibits the reaction [Acrolein results in increased expression of IL6 mRNA]; Acetylcysteine inhibits the reaction [Lipopolysaccharides promotes the reaction [Acrolein results in increased expression of IL6 mRNA]]; Acrolein promotes the reaction [Lipopolysaccharides results in increased expression of IL6 mRNA]; Apigenin analog inhibits the reaction [Acrolein promotes the reaction [Lipopolysaccharides results in increased expression of IL6 mRNA]]; Apigenin analog inhibits the reaction [Lipopolysaccharides promotes the reaction [Acrolein results in increased expression of IL6 mRNA]]; Apigenin inhibits the reaction [Acrolein promotes the reaction [Lipopolysaccharides results in increased expression of IL6 mRNA]]; Apigenin inhibits the reaction [Lipopolysaccharides promotes the reaction [Acrolein results in increased expression of IL6 mRNA]]; Lipopolysaccharides promotes the reaction [Acrolein results in increased expression of IL6 mRNA]; Phenylbutyrates inhibits the reaction [Acrolein results in increased expression of IL6 mRNA]; ST2825 inhibits the reaction [Acrolein results in increased expression of IL6 protein] | PMID:16860297 PMID:18951912 PMID:36055550 | IL6 | increases expression | ISO | Il6 (Rattus norvegicus) | 6480464 | CTD | Acrolein results in increased expression of IL6 mRNA; Acrolein results in increased expression of IL6 protein | PMID:21265103 PMID:22961095 PMID:25145656 | IL6 | multiple interactions | ISO | Il6 (Rattus norvegicus) | 6480464 | CTD | Enalapril inhibits the reaction [Acrolein results in increased expression of IL6 mRNA]; Enalapril inhibits the reaction [Acrolein results in increased expression of IL6 protein] | PMID:21265103 | | ||||||||||||||||||||||
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