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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 11419
Species: Mus musculus
RGD Object: Gene
Symbol: Timp3
Name: tissue inhibitor of metalloproteinase 3
Acc ID: CHEBI:15368
Term: acrolein
Definition: An enal that is prop-2-ene with an oxo group at position 1.
Chemical ID: MESH:D000171
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Timp3decreases expressionEXP 6480464CTDAcrolein results in decreased expression of TIMP3 mRNAPMID:18006877
Timp3decreases expressionISOTIMP3 (Homo sapiens)6480464CTDAcrolein results in decreased expression of TIMP3 mRNAPMID:15531749 PMID:21742783
Timp3multiple interactionsISOTIMP3 (Homo sapiens)6480464CTDTIMP3 protein inhibits the reaction [Acrolein results in increased expression of MUC5AC mRNA]PMID:15531749
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