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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 10473
Species: Mus musculus
RGD Object: Gene
Symbol: Nqo1
Name: NAD(P)H dehydrogenase, quinone 1
Acc ID: CHEBI:15368
Term: acrolein
Definition: An enal that is prop-2-ene with an oxo group at position 1.
Chemical ID: MESH:D000171
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Nqo1increases expressionEXP 6480464CTDAcrolein results in increased expression of NQO1 mRNAPMID:12763045
Nqo1increases expressionISONqo1 (Rattus norvegicus)6480464CTDAcrolein results in increased expression of NQO1 mRNAPMID:25145656
Nqo1increases expressionISONQO1 (Homo sapiens)6480464CTDAcrolein results in increased expression of NQO1 mRNA; Acrolein results in increased expression of NQO1 proteinPMID:12084617 PMID:20015449 PMID:24211530
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