GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | Bcl2 | decreases expression | EXP | | 6480464 | CTD | Acrolein results in decreased expression of BCL2 protein | PMID:24376112 | Bcl2 | multiple interactions | EXP | | 6480464 | CTD | capsazepine inhibits the reaction [Acrolein results in decreased expression of BCL2 protein]; Glutathione inhibits the reaction [Acrolein results in decreased expression of BCL2 protein] | PMID:24376112 | Bcl2 | decreases expression | ISO | Bcl2 (Rattus norvegicus) | 6480464 | CTD | Acrolein results in decreased expression of BCL2 mRNA; Acrolein results in decreased expression of BCL2 protein | PMID:29414845 | Bcl2 | decreases expression | ISO | BCL2 (Homo sapiens) | 6480464 | CTD | Acrolein results in decreased expression of BCL2 protein | PMID:34958888 | Bcl2 | multiple interactions | ISO | Bcl2 (Rattus norvegicus) | 6480464 | CTD | 3,4-dihydroxyphenylethanol inhibits the reaction [Acrolein results in decreased expression of BCL2 mRNA]; 3,4-dihydroxyphenylethanol inhibits the reaction [Acrolein results in decreased expression of BCL2 protein]; [Acrolein results in increased susceptibility to Isoproterenol] which results in decreased expression of BCL2 protein; Acrolein promotes the reaction [Isoproterenol results in decreased expression of BCL2 mRNA]; oleuropein inhibits the reaction [Acrolein results in decreased expression of BCL2 mRNA]; oleuropein inhibits the reaction [Acrolein results in decreased expression of BCL2 protein]; Plant Extracts inhibits the reaction [[Acrolein results in increased susceptibility to Isoproterenol] which results in decreased expression of BCL2 protein]; Plant Extracts inhibits the reaction [Acrolein promotes the reaction [Isoproterenol results in decreased expression of BCL2 mRNA]] | PMID:29414845 | |
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