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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 736819
Species: Homo sapiens
RGD Object: Gene
Symbol: ID1
Name: inhibitor of DNA binding 1
Acc ID: CHEBI:15367
Term: all-trans-retinoic acid
Definition: A retinoic acid in which all four exocyclic double bonds have E- (trans-) geometry.
Chemical ID: MESH:D014212
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
ID1increases expressionEXP 6480464CTDTretinoin results in increased expression of ID1 mRNA; Tretinoin results in increased expression of ID1 proteinPMID:16054129 PMID:16249480 PMID:16494909 PMID:21934132 PMID:23724009 PMID:23830798 PMID:33167477
ID1multiple interactionsEXP 6480464CTDDactinomycin inhibits the reaction [Tretinoin results in increased expression of ID1 mRNA]PMID:16494909
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