Send us a Message
Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   
Search RGD Grant Resources Citing RGD About Us Contact Us
Genes Variants Community Projects QTLs Strains Markers Genome Information Ontologies Cell Lines References Download Submit Data
OntoMate (Literature Search) JBrowse (Genome Browser) Synteny Browser (VCMap) Variant Visualizer Multi-Ontology Enrichment (MOET) Gene-Ortholog Location Finder (GOLF) InterViewer (Protein-Protein Interactions) PhenoMiner (Quatitative Phenotypes) Gene Annotator OLGA (Gene List Generator) AllianceMine GViewer (Genome Viewer)
Aging & Age-Related Disease Cancer & Neoplastic Disease Cardiovascular Disease Coronavirus Disease Developmental Disease Diabetes Hematologic Disease Immune & Inflammatory Disease Infectious Disease Liver Disease Neurological Disease Obesity & Metabolic Syndrome Renal Disease Respiratory Disease Sensory Organ Disease
Find Models   new Genetic Models Autism Models Rat PhenoMiner (Quantitative Phenotypes) Chinchilla PhenoMiner Expected Ranges (Quantitative Phenotype) PhenoMiner Term Comparison Hybrid Rat Diversity Panel Phenotypes Phenotypes in Other Animal Models Animal Husbandry Strain Medical Records Phylogenetics Strain Availability Calendar Rats 101 Submissions Photo Archive
Pathways
Rat Community Forum Directory of Rat Laboratories Video Tutorials News RGD Publications RGD Presentations Archive Nomenclature Guidelines Resource Links Laboratory Resources Employment Resources

GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 736208
Species: Homo sapiens
RGD Object: Gene
Symbol: CEBPB
Name: CCAAT enhancer binding protein beta
Acc ID: CHEBI:15367
Term: all-trans-retinoic acid
Definition: A retinoic acid in which all four exocyclic double bonds have E- (trans-) geometry.
Chemical ID: MESH:D014212
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
CEBPBaffects localizationEXP 6480464CTDTretinoin affects the localization of CEBPB proteinPMID:16608438
CEBPBincreases activityEXP 6480464CTDTretinoin results in increased activity of CEBPB protein alternative formPMID:16608438
CEBPBincreases expressionEXP 6480464CTDTretinoin results in increased expression of CEBPB mRNA; Tretinoin results in increased expression of CEBPB protein; Tretinoin results in increased expression of CEBPB protein alternative formPMID:15498508 PMID:15894607 PMID:16608438 PMID:17218384 PMID:17656649 PMID:30076181 PMID:33167477 PMID:33609515
CEBPBmultiple interactionsEXP 6480464CTD2-bromopalmitate promotes the reaction [Tretinoin results in increased expression of CEBPB mRNA]; [Tretinoin co-treated with Arsenic Trioxide] results in increased expression of CEBPB mRNA; [Tretinoin co-treated with CXCL12 protein] results in increased expression of CEBPB protein; Tretinoin inhibits the reaction [DAXX protein binds to CEBPB protein]; Tretinoin promotes the reaction [CEBPB protein binds to CXCL12 promoter]; Tretinoin promotes the reaction [CEBPB protein binds to SPI1 promoter]PMID:15894607 PMID:16352814 PMID:17656649 PMID:19690170 PMID:30076181
CEBPBincreases expressionISOCebpb (Rattus norvegicus)6480464CTDTretinoin results in increased expression of CEBPB mRNA; Tretinoin results in increased expression of CEBPB proteinPMID:14568882 PMID:24977338
Go Back to source page   Continue to Ontology report