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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 733158
Species: Mus musculus
RGD Object: Gene
Symbol: Tgfb3
Name: transforming growth factor, beta 3
Acc ID: CHEBI:15367
Term: all-trans-retinoic acid
Definition: A retinoic acid in which all four exocyclic double bonds have E- (trans-) geometry.
Chemical ID: MESH:D014212
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Tgfb3affects expressionEXP 6480464CTDTretinoin affects the expression of TGFB3 mRNAPMID:16235736
Tgfb3increases expressionEXP 6480464CTDTretinoin results in increased expression of TGFB3 mRNAPMID:12834868 PMID:16410076
Tgfb3multiple interactionsEXP 6480464CTD[bisphenol F co-treated with Tretinoin] results in decreased expression of TGFB3 mRNA; [bisphenol S co-treated with Tretinoin] results in decreased expression of TGFB3 mRNAPMID:30951980
Tgfb3decreases expressionISOTGFB3 (Homo sapiens)6480464CTDTretinoin results in decreased expression of TGFB3; Tretinoin results in decreased expression of TGFB3 mRNAPMID:23830798 PMID:24374174
Tgfb3multiple interactionsISOTGFB3 (Homo sapiens)6480464CTDTGFB3 protein inhibits the reaction [Tretinoin results in decreased expression of FBN2]; TGFB3 protein inhibits the reaction [Tretinoin results in decreased expression of FN1]; TGFB3 protein inhibits the reaction [Tretinoin results in decreased expression of TNC]PMID:24374174
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