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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 733129
Species: Mus musculus
RGD Object: Gene
Symbol: Vim
Name: vimentin
Acc ID: CHEBI:15367
Term: all-trans-retinoic acid
Definition: A retinoic acid in which all four exocyclic double bonds have E- (trans-) geometry.
Chemical ID: MESH:D014212
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Vimdecreases expressionEXP 6480464CTDTretinoin results in decreased expression of VIM mRNAPMID:16604517
Vimdecreases expressionISOVIM (Homo sapiens)6480464CTDTretinoin results in decreased expression of VIM mRNA; Tretinoin results in decreased expression of VIM proteinPMID:15498508 PMID:16129123 PMID:17045167 PMID:17218384 PMID:23724009 PMID:28886987 PMID:30093655 PMID:30806631 PMID:31634547 PMID:33167477 PMID:36805303
Vimmultiple interactionsISOVIM (Homo sapiens)6480464CTD[Tretinoin co-treated with Alitretinoin] results in decreased expression of VIM mRNA; [Tretinoin co-treated with tributyltinisothiocyanate] results in decreased expression of VIM mRNA; [Tretinoin co-treated with triphenyltin analog] results in decreased expression of VIM mRNA; [Tretinoin co-treated with triphenyltin chloride] results in decreased expression of VIM mRNA; Arsenic Trioxide promotes the reaction [Tretinoin results in decreased expression of VIM mRNA]; Tretinoin promotes the reaction [Alitretinoin results in decreased expression of VIM protein]; Tretinoin promotes the reaction [Arsenic Trioxide results in decreased expression of VIM mRNA]; Tretinoin promotes the reaction [tributyltin results in decreased expression of VIM mRNA]; Tretinoin promotes the reaction [tributyltin results in decreased expression of VIM protein]; Tretinoin promotes the reaction [tributyltinisothiocyanate results in decreased expression of VIM protein]; Tretinoin promotes the reaction [triphenyltin analog results in decreased expression of VIM protein]; Tretinoin promotes the reaction [triphenyltin chloride results in decreased expression of VIM protein]PMID:30093655 PMID:30806631 PMID:31634547
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