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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 732481
Species: Mus musculus
RGD Object: Gene
Symbol: Hspb1
Name: heat shock protein 1
Acc ID: CHEBI:15367
Term: all-trans-retinoic acid
Definition: A retinoic acid in which all four exocyclic double bonds have E- (trans-) geometry.
Chemical ID: MESH:D014212
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Hspb1increases expressionEXP 6480464CTDTretinoin results in increased expression of HSPB1 mRNAPMID:20117194
Hspb1multiple interactionsEXP 6480464CTD[bisphenol F co-treated with Tretinoin] results in decreased expression of HSPB1 mRNA; [bisphenol S co-treated with Tretinoin] results in decreased expression of HSPB1 mRNAPMID:30951980
Hspb1decreases expressionISOHSPB1 (Homo sapiens)6480464CTDTretinoin results in decreased expression of HSPB1 mRNAPMID:21934132 PMID:33167477
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