GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | MAP2K1 | decreases expression | EXP | | 6480464 | CTD | Tretinoin results in decreased expression of MAP2K1 protein | PMID:18098270 | MAP2K1 | increases phosphorylation | EXP | | 6480464 | CTD | Tretinoin results in increased phosphorylation of MAP2K1 protein | PMID:19038232 | MAP2K1 | multiple interactions | EXP | | 6480464 | CTD | 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [arsenic trioxide promotes the reaction [Tretinoin results in increased phosphorylation of and results in increased activity of MAP2K1 protein]]; 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [Tretinoin results in increased phosphorylation of and results in increased activity of MAP2K1 protein]; [Tretinoin co-treated with Paclitaxel] results in decreased expression of MAP2K1 protein; arsenic trioxide promotes the reaction [Tretinoin results in increased phosphorylation of and results in increased activity of MAP2K1 protein]; Tretinoin results in increased phosphorylation of and results in increased activity of MAP2K1 protein | PMID:18098270 PMID:20615082 | | ||||||||||||||||||||||
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