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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 731429
Species: Homo sapiens
RGD Object: Gene
Symbol: ITGA6
Name: integrin subunit alpha 6
Acc ID: CHEBI:15367
Term: all-trans-retinoic acid
Definition: A retinoic acid in which all four exocyclic double bonds have E- (trans-) geometry.
Chemical ID: MESH:D014212
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
ITGA6increases expressionEXP 6480464CTDTretinoin results in increased expression of ITGA6 mRNAPMID:16054129 PMID:16140955 PMID:33167477
ITGA6multiple interactionsEXP 6480464CTD[Tretinoin co-treated with arsenic trioxide] results in decreased expression of ITGA6 mRNA; Thiophenes analog promotes the reaction [Tretinoin results in increased expression of ITGA6 mRNA]PMID:15894607 PMID:16140955
ITGA6decreases expressionISOItga6 (Mus musculus)6480464CTDTretinoin results in decreased expression of ITGA6 mRNAPMID:10748128
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