GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | Gjb2 | increases expression | ISO | GJB2 (Homo sapiens) | 6480464 | CTD | Tretinoin results in increased expression of GJB2 mRNA | PMID:16029656 PMID:21934132 | Gjb2 | multiple interactions | ISO | GJB2 (Homo sapiens) | 6480464 | CTD | Tretinoin promotes the reaction [[GJB1 protein co-treated with GJB2 protein] promotes the reaction [Cisplatin results in increased activity of CASP3 protein]]; Tretinoin promotes the reaction [[GJB1 protein co-treated with GJB2 protein] promotes the reaction [Cisplatin results in increased activity of CASP9 protein]] | PMID:23747833 | Gjb2 | multiple interactions | ISO | Gjb2 (Mus musculus) | 6480464 | CTD | [bisphenol A co-treated with Tretinoin] results in increased expression of GJB2 mRNA | PMID:30951980 | | ||||||||||||||||||||||
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