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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 69453
Species: Homo sapiens
RGD Object: Gene
Symbol: LCN2
Name: lipocalin 2
Acc ID: CHEBI:15367
Term: all-trans-retinoic acid
Definition: A retinoic acid in which all four exocyclic double bonds have E- (trans-) geometry.
Chemical ID: MESH:D014212
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
LCN2increases expressionEXP 6480464CTDTretinoin metabolite results in increased expression of LCN2 mRNA; Tretinoin results in increased expression of LCN2 mRNA; Tretinoin results in increased expression of LCN2 proteinPMID:15982314 PMID:16249480 PMID:16671099 PMID:23830798
LCN2increases secretionEXP 6480464CTDTretinoin results in increased secretion of LCN2 proteinPMID:16671099
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