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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 69305
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Nr2f2
Name: nuclear receptor subfamily 2, group F, member 2
Acc ID: CHEBI:15367
Term: all-trans-retinoic acid
Definition: A retinoic acid in which all four exocyclic double bonds have E- (trans-) geometry.
Chemical ID: MESH:D014212
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Nr2f2decreases expressionISONR2F2 (Homo sapiens)6480464CTDTretinoin results in decreased expression of NR2F2 mRNAPMID:15498508 PMID:33167477
Nr2f2increases expressionISONR2F2 (Homo sapiens)6480464CTDTretinoin results in increased expression of NR2F2 mRNA; Tretinoin results in increased expression of NR2F2 proteinPMID:21934132 PMID:22906706 PMID:23830798 PMID:30416051
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