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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 69143
Species: Mus musculus
RGD Object: Gene
Symbol: Mdk
Name: midkine
Acc ID: CHEBI:15367
Term: all-trans-retinoic acid
Definition: A retinoic acid in which all four exocyclic double bonds have E- (trans-) geometry.
Chemical ID: MESH:D014212
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Mdkincreases expressionEXP 6480464CTDTretinoin results in increased expression of MDK mRNAPMID:16604517
Mdkincreases expressionISOMDK (Homo sapiens)6480464CTDTretinoin results in increased expression of MDK mRNAPMID:17138961 PMID:23724009 PMID:23830798
Mdkmultiple interactionsISOMdk (Rattus norvegicus)6480464CTDTretinoin inhibits the reaction [Puromycin Aminonucleoside results in decreased expression of MDK mRNA]PMID:12660332
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