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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 621714
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Sptan1
Name: spectrin, alpha, non-erythrocytic 1
Acc ID: CHEBI:15367
Term: all-trans-retinoic acid
Definition: A retinoic acid in which all four exocyclic double bonds have E- (trans-) geometry.
Chemical ID: MESH:D014212
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Sptan1decreases expressionISOSPTAN1 (Homo sapiens)6480464CTDTretinoin results in decreased expression of SPTAN1 mRNAPMID:33167477
Sptan1multiple interactionsISOSPTAN1 (Homo sapiens)6480464CTD[IFNB1 protein co-treated with Tretinoin] results in increased cleavage of SPTAN1 proteinPMID:16826196
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