GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | Ret | increases expression | EXP | | 6480464 | CTD | Tretinoin results in increased expression of RET mRNA | PMID:20488242 | Ret | decreases expression | ISO | RET (Homo sapiens) | 6480464 | CTD | Tretinoin results in decreased expression of RET mRNA | PMID:33167477 | Ret | increases expression | ISO | RET (Homo sapiens) | 6480464 | CTD | Tretinoin results in increased expression of RET mRNA; Tretinoin results in increased expression of RET protein | PMID:16012519 PMID:17431108 PMID:17435603 PMID:21934132 PMID:23724009 | Ret | increases phosphorylation | ISO | RET (Homo sapiens) | 6480464 | CTD | Tretinoin results in increased phosphorylation of RET protein | PMID:17431108 | Ret | increases response to substance | ISO | RET (Homo sapiens) | 6480464 | CTD | RET protein results in increased susceptibility to Tretinoin | PMID:16849523 | Ret | multiple interactions | ISO | RET (Homo sapiens) | 6480464 | CTD | [Tretinoin results in increased secretion of GDNF protein] which results in increased activity of RET protein; Tretinoin results in increased expression of and results in increased phosphorylation of and results in increased activity of RET protein | PMID:16849523 | |
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