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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 3543
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Rbp1
Name: retinol binding protein 1
Acc ID: CHEBI:15367
Term: all-trans-retinoic acid
Definition: A retinoic acid in which all four exocyclic double bonds have E- (trans-) geometry.
Chemical ID: MESH:D014212
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Rbp1affects expressionEXP 6480464CTDTretinoin affects the expression of RBP1 mRNAPMID:22262565
Rbp1increases expressionEXP 6480464CTDTretinoin results in increased expression of RBP1 mRNAPMID:26672737 PMID:30329139 PMID:30476341
Rbp1multiple interactionsEXP 6480464CTDTretinoin inhibits the reaction [Ethinyl Estradiol results in decreased expression of RBP1 mRNA]; Tretinoin promotes the reaction [nitrofen results in increased expression of RBP1 mRNA]PMID:17161848 PMID:26672737
Rbp1increases expressionISORbp1 (Mus musculus)6480464CTDTretinoin results in increased expression of RBP1 mRNAPMID:16505366 PMID:16604517 PMID:36189433
Rbp1increases expressionISORBP1 (Homo sapiens)6480464CTDTretinoin results in increased expression of RBP1 mRNAPMID:16012519 PMID:16249480 PMID:17079450 PMID:17431108 PMID:21934132 PMID:23724009 PMID:7556191
Rbp1multiple interactionsISORbp1 (Mus musculus)6480464CTD[mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in increased expression of RBP1 mRNAPMID:36189433
Rbp1multiple interactionsISORBP1 (Homo sapiens)6480464CTDDecitabine promotes the reaction [Tretinoin results in increased expression of RBP1 mRNA]; Tretinoin promotes the reaction [H4C16 protein modified form binds to RBP1 gene]; Tretinoin promotes the reaction [RARB protein alternative form binds to RBP1 promoter]PMID:17079450
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