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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 2664
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Gata2
Name: GATA binding protein 2
Acc ID: CHEBI:15367
Term: all-trans-retinoic acid
Definition: A retinoic acid in which all four exocyclic double bonds have E- (trans-) geometry.
Chemical ID: MESH:D014212
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Gata2decreases expressionISOGATA2 (Homo sapiens)6480464CTDTretinoin results in decreased expression of GATA2 mRNA; Tretinoin results in decreased expression of GATA2 proteinPMID:15498508 PMID:18922099 PMID:33167477
Gata2increases expressionISOGATA2 (Homo sapiens)6480464CTDTretinoin results in increased expression of GATA2 mRNAPMID:17138961
Gata2multiple interactionsISOGata2 (Mus musculus)6480464CTD[bisphenol F co-treated with Tretinoin] results in decreased expression of GATA2 mRNA; [bisphenol S co-treated with Tretinoin] results in decreased expression of GATA2 mRNAPMID:30951980
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