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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1605110
Species: Homo sapiens
RGD Object: Gene
Symbol: KEAP1
Name: kelch like ECH associated protein 1
Acc ID: CHEBI:15367
Term: all-trans-retinoic acid
Definition: A retinoic acid in which all four exocyclic double bonds have E- (trans-) geometry.
Chemical ID: MESH:D014212
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
KEAP1multiple interactionsEXP 6480464CTD[Tretinoin co-treated with arsenic trioxide] results in increased expression of KEAP1 mRNAPMID:15894607
KEAP1increases expressionISOKeap1 (Rattus norvegicus)6480464CTDTretinoin results in increased expression of KEAP1 proteinPMID:30267739
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