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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1604844
Species: Homo sapiens
RGD Object: Gene
Symbol: TP63
Name: tumor protein p63
Acc ID: CHEBI:15367
Term: all-trans-retinoic acid
Definition: A retinoic acid in which all four exocyclic double bonds have E- (trans-) geometry.
Chemical ID: MESH:D014212
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
TP63multiple interactionsEXP 6480464CTD[Tretinoin co-treated with BMP4 protein] results in increased expression of TP63 proteinPMID:30397335
TP63decreases expressionISOTrp63 (Mus musculus)6480464CTDTretinoin results in decreased expression of TRP63 mRNA alternative formPMID:16998800
TP63multiple interactionsISOTrp63 (Mus musculus)6480464CTD[mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in decreased expression of TRP63 mRNAPMID:36189433
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