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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1351014
Species: Homo sapiens
RGD Object: Gene
Symbol: CTSD
Name: cathepsin D
Acc ID: CHEBI:15367
Term: all-trans-retinoic acid
Definition: A retinoic acid in which all four exocyclic double bonds have E- (trans-) geometry.
Chemical ID: MESH:D014212
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
CTSDincreases expressionEXP 6480464CTDTretinoin results in increased expression of CTSD mRNA; Tretinoin results in increased expression of CTSD proteinPMID:15498508 PMID:16054129 PMID:17218384 PMID:23864846 PMID:33167477
CTSDmultiple interactionsEXP 6480464CTDTretinoin promotes the reaction [AG 1879 results in increased expression of CTSD protein]PMID:23864846
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