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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1350844
Species: Homo sapiens
RGD Object: Gene
Symbol: NR0B1
Name: nuclear receptor subfamily 0 group B member 1
Acc ID: CHEBI:15367
Term: all-trans-retinoic acid
Definition: A retinoic acid in which all four exocyclic double bonds have E- (trans-) geometry.
Chemical ID: MESH:D014212
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
NR0B1increases expressionEXP 6480464CTDTretinoin results in increased expression of NR0B1 mRNAPMID:21934132
NR0B1decreases expressionISONr0b1 (Mus musculus)6480464CTDTretinoin results in decreased expression of NR0B1 mRNAPMID:16604517
NR0B1increases expressionISONr0b1 (Rattus norvegicus)6480464CTDTretinoin results in increased expression of NR0B1 mRNAPMID:30329139 PMID:30476341
NR0B1increases expressionISONr0b1 (Mus musculus)6480464CTDTretinoin results in increased expression of NR0B1 mRNAPMID:36189433
NR0B1multiple interactionsISONr0b1 (Rattus norvegicus)6480464CTDmono-(2-ethylhexyl)phthalate promotes the reaction [Tretinoin results in increased expression of NR0B1 mRNA]PMID:30476341
NR0B1multiple interactionsISONr0b1 (Mus musculus)6480464CTD[mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in increased expression of NR0B1 mRNAPMID:36189433
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