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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1349908
Species: Homo sapiens
RGD Object: Gene
Symbol: PRAME
Name: PRAME nuclear receptor transcriptional regulator
Acc ID: CHEBI:15367
Term: all-trans-retinoic acid
Definition: A retinoic acid in which all four exocyclic double bonds have E- (trans-) geometry.
Chemical ID: MESH:D014212
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
PRAMEdecreases activityEXP 6480464CTDPRAME protein results in decreased activity of TretinoinPMID:16179254
PRAMEmultiple interactionsEXP 6480464CTDTretinoin promotes the reaction [RARA protein binds to PRAME protein]PMID:16179254
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