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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1348968
Species: Homo sapiens
RGD Object: Gene
Symbol: ITGAX
Name: integrin subunit alpha X
Acc ID: CHEBI:15367
Term: all-trans-retinoic acid
Definition: A retinoic acid in which all four exocyclic double bonds have E- (trans-) geometry.
Chemical ID: MESH:D014212
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
ITGAXincreases expressionEXP 6480464CTDTretinoin results in increased expression of ITGAX mRNA; Tretinoin results in increased expression of ITGAX proteinPMID:15770638 PMID:15988048 PMID:16764927 PMID:17361223 PMID:33167477
ITGAXmultiple interactionsEXP 6480464CTDLAT2 protein inhibits the reaction [Tretinoin results in increased expression of ITGAX protein]PMID:32587277
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