GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | FAS | decreases expression | EXP | | 6480464 | CTD | Tretinoin results in decreased expression of FAS mRNA; Tretinoin results in decreased expression of FAS protein | PMID:16510162 PMID:17034753 | FAS | increases activity | EXP | | 6480464 | CTD | Tretinoin results in increased activity of FAS protein | PMID:15703382 | FAS | increases expression | EXP | | 6480464 | CTD | Tretinoin results in increased expression of FAS mRNA; Tretinoin results in increased expression of FAS protein | PMID:16712844 PMID:16957513 PMID:20629322 PMID:34742744 | FAS | multiple interactions | EXP | | 6480464 | CTD | [IFNG protein co-treated with Tretinoin] results in increased expression of FAS mRNA; [IFNG protein co-treated with Tretinoin] results in increased expression of FAS protein; [Tretinoin co-treated with Zoledronic Acid] results in increased expression of FAS protein; CYP26A1 protein inhibits the reaction [Tretinoin results in increased activity of FAS protein]; Ketoconazole inhibits the reaction [CYP26A1 protein inhibits the reaction [Tretinoin results in increased activity of FAS protein]] | PMID:15703382 PMID:16136269 PMID:20349282 | FAS | multiple interactions | ISO | Fas (Mus musculus) | 6480464 | CTD | [bisphenol F co-treated with Tretinoin] results in decreased expression of FAS mRNA | PMID:30951980 | |
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