GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | TNFSF10 | increases activity | EXP | | 6480464 | CTD | Tretinoin results in increased activity of TNFSF10 protein | PMID:15703382 | TNFSF10 | increases expression | EXP | | 6480464 | CTD | Tretinoin results in increased expression of TNFSF10 mRNA; Tretinoin results in increased expression of TNFSF10 protein | PMID:11385504 PMID:16140955 PMID:16242776 PMID:23830798 PMID:33167477 | TNFSF10 | multiple interactions | EXP | | 6480464 | CTD | CYP26A1 protein inhibits the reaction [Tretinoin results in increased activity of TNFSF10 protein]; Ketoconazole inhibits the reaction [CYP26A1 protein inhibits the reaction [Tretinoin results in increased activity of TNFSF10 protein]]; TGFB1 protein inhibits the reaction [Tretinoin results in increased expression of TNFSF10 protein]; Thiophenes analog promotes the reaction [Tretinoin results in increased expression of TNFSF10 mRNA]; Tretinoin promotes the reaction [IFNG protein promotes the reaction [IRF1 protein results in increased expression of TNFSF10 mRNA]]; Tretinoin promotes the reaction [IFNG protein results in increased expression of TNFSF10 mRNA] | PMID:15703382 PMID:16085646 PMID:16140955 PMID:16242776 | | ||||||||||||||||||||||
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