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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1321120
Species: Mus musculus
RGD Object: Gene
Symbol: Hoxb1
Name: homeobox B1
Acc ID: CHEBI:15367
Term: all-trans-retinoic acid
Definition: A retinoic acid in which all four exocyclic double bonds have E- (trans-) geometry.
Chemical ID: MESH:D014212
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Hoxb1affects localizationEXP 6480464CTDTretinoin affects the localization of HOXB1 proteinPMID:9184346
Hoxb1increases expressionEXP 6480464CTDTretinoin results in increased expression of HOXB1 mRNAPMID:16038797 PMID:16604517 PMID:16845368 PMID:36189433
Hoxb1multiple interactionsEXP 6480464CTD[mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in increased expression of HOXB1 mRNAPMID:36189433
Hoxb1affects expressionISOHOXB1 (Homo sapiens)6480464CTDTretinoin affects the expression of HOXB1 mRNAPMID:31600526
Hoxb1increases expressionISOHOXB1 (Homo sapiens)6480464CTDTretinoin results in increased expression of HOXB1 mRNAPMID:21934132 PMID:34742744
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