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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1307083
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Tp73
Name: tumor protein p73
Acc ID: CHEBI:15367
Term: all-trans-retinoic acid
Definition: A retinoic acid in which all four exocyclic double bonds have E- (trans-) geometry.
Chemical ID: MESH:D014212
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Tp73increases expressionISOTP73 (Homo sapiens)6480464CTDTretinoin results in increased expression of TRP73 proteinPMID:24190996
Tp73multiple interactionsISOTP73 (Homo sapiens)6480464CTDTP73 protein affects the reaction [Tretinoin promotes the reaction [bafilomycin A results in increased expression of MAP1LC3B protein modified form]]; TP73 protein affects the reaction [Tretinoin results in increased expression of DAPK2 mRNA]; TP73 protein affects the reaction [Tretinoin results in increased expression of DAPK2 protein]PMID:28978663
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