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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1302955
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Ddah2
Name: DDAH family member 2, ADMA-independent
Acc ID: CHEBI:15367
Term: all-trans-retinoic acid
Definition: A retinoic acid in which all four exocyclic double bonds have E- (trans-) geometry.
Chemical ID: MESH:D014212
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Ddah2multiple interactionsEXP 6480464CTDDDAH2 protein promotes the reaction [Tretinoin inhibits the reaction [cobaltous chloride results in increased activity of CASP3 protein]]; Tretinoin inhibits the reaction [cobaltous chloride results in decreased expression of DDAH2 mRNA]; Tretinoin inhibits the reaction [cobaltous chloride results in decreased expression of DDAH2 protein]PMID:19156866
Ddah2decreases expressionISODDAH2 (Homo sapiens)6480464CTDTretinoin results in decreased expression of DDAH2 mRNAPMID:17218384
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