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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1299953
Species: Homo sapiens
RGD Object: Gene
Symbol: ZEB1
Name: zinc finger E-box binding homeobox 1
Acc ID: CHEBI:15367
Term: all-trans-retinoic acid
Definition: A retinoic acid in which all four exocyclic double bonds have E- (trans-) geometry.
Chemical ID: MESH:D014212
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
ZEB1decreases expressionEXP 6480464CTDTretinoin results in decreased expression of ZEB1 mRNAPMID:21934132 PMID:30093655
ZEB1multiple interactionsEXP 6480464CTDArsenic Trioxide promotes the reaction [Tretinoin results in decreased expression of ZEB1 mRNA]; Tretinoin promotes the reaction [Arsenic Trioxide results in decreased expression of ZEB1 mRNA]PMID:30093655
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