Gene Chemical Interaction Report - Rat Genome Database

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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID:	12244264
Species:	Canis lupus familiaris
RGD Object:	Gene
Symbol:	OCLN
Name:	occludin

Acc ID:	CHEBI:15367
Term:	all-trans-retinoic acid
Definition:	A retinoic acid in which all four exocyclic double bonds have E- (trans-) geometry.
Chemical ID:	MESH:D014212

Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.

Object Symbol	Qualifier	Evidence	With	Reference	Source	Notes	Original Reference(s)
OCLN	increases expression	EXP		6480464	CTD	Tretinoin results in increased expression of OCLN mRNA; Tretinoin results in increased expression of OCLN protein	PMID:17035595
OCLN	multiple interactions	EXP		6480464	CTD	CYP26A1 protein inhibits the reaction [Tretinoin results in increased expression of OCLN mRNA]	PMID:17035595

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