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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 11069
Species: Mus musculus
RGD Object: Gene
Symbol: Pdgfra
Name: platelet derived growth factor receptor, alpha polypeptide
Acc ID: CHEBI:15367
Term: all-trans-retinoic acid
Definition: A retinoic acid in which all four exocyclic double bonds have E- (trans-) geometry.
Chemical ID: MESH:D014212
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Pdgfradecreases expressionEXP 6480464CTDTretinoin results in decreased expression of PDGFRA proteinPMID:16956736
Pdgfraincreases expressionEXP 6480464CTDTretinoin results in increased expression of PDGFRA mRNAPMID:16604517
Pdgframultiple interactionsEXP 6480464CTD[bisphenol A co-treated with Tretinoin] results in decreased expression of PDGFRA mRNA; [bisphenol F co-treated with Tretinoin] results in decreased expression of PDGFRA mRNAPMID:30951980
Pdgfraincreases expressionISOPDGFRA (Homo sapiens)6480464CTDTretinoin results in increased expression of PDGFRA mRNAPMID:21934132 PMID:23724009
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