GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | Myc | decreases expression | EXP | | 6480464 | CTD | Tretinoin results in decreased expression of MYC mRNA | PMID:16604517 PMID:16788091 | Myc | increases expression | EXP | | 6480464 | CTD | Tretinoin results in increased expression of MYC mRNA | PMID:26272751 | Myc | multiple interactions | EXP | | 6480464 | CTD | NR2C1 protein affects the reaction [Tretinoin results in increased expression of MYC protein] | PMID:17389641 | Myc | affects expression | ISO | MYC (Homo sapiens) | 6480464 | CTD | Tretinoin affects the expression of MYC protein | PMID:16054129 | Myc | decreases expression | ISO | Myc (Rattus norvegicus) | 6480464 | CTD | Tretinoin results in decreased expression of MYC protein | PMID:1917145 | Myc | decreases expression | ISO | MYC (Homo sapiens) | 6480464 | CTD | Tretinoin results in decreased expression of MYC mRNA; Tretinoin results in decreased expression of MYC protein | PMID:12875902 PMID:15498508 PMID:15770638 PMID:16054129 PMID:16140955 PMID:17218384 PMID:17229153 PMID:17318229 PMID:17453147 PMID:20945414 PMID:21924320 PMID:23724009 PMID:23830798 PMID:30093655 PMID:33167477 | Myc | multiple interactions | ISO | MYC (Homo sapiens) | 6480464 | CTD | [Arsenic Trioxide co-treated with Tretinoin] results in decreased expression of MYC protein; Arsenic Trioxide promotes the reaction [Tretinoin results in decreased expression of MYC protein]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde promotes the reaction [Tretinoin results in decreased expression of MYC protein]; Thiophenes analog promotes the reaction [Tretinoin results in decreased expression of MYC mRNA]; Tretinoin promotes the reaction [Arsenic Trioxide results in decreased expression of MYC protein] | PMID:16140955 PMID:20945414 PMID:30093655 | |
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