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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 2138
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Apoe
Name: apolipoprotein E
Acc ID: CHEBI:15355
Term: acetylcholine
Definition: Actylcholine is an ester of acetic acid and choline, which acts as a neurotransmitter.
Chemical ID: MESH:D000109
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Apoeaffects response to substanceISOApoe (Mus musculus)6480464CTDAPOE protein affects the susceptibility to AcetylcholinePMID:17899169
Apoedecreases response to substanceISOApoe (Mus musculus)6480464CTDAPOE gene mutant form results in decreased susceptibility to AcetylcholinePMID:11397713
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