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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 10499
Species: Mus musculus
RGD Object: Gene
Symbol: Edn1
Name: endothelin 1
Acc ID: CHEBI:15355
Term: acetylcholine
Definition: Actylcholine is an ester of acetic acid and choline, which acts as a neurotransmitter.
Chemical ID: MESH:D000109
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Edn1decreases response to substanceISOEdn1 (Rattus norvegicus)6480464CTDEDN1 protein results in decreased susceptibility to AcetylcholinePMID:20977430
Edn1multiple interactionsISOEdn1 (Rattus norvegicus)6480464CTDacetovanillone inhibits the reaction [EDN1 protein results in decreased susceptibility to Acetylcholine]; Catechin inhibits the reaction [EDN1 protein results in decreased susceptibility to Acetylcholine]; Polyphenols inhibits the reaction [EDN1 protein results in decreased susceptibility to Acetylcholine]PMID:20977430
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