GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | PPARA | multiple interactions | EXP | | 6480464 | CTD | 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [[Methionine deficiency co-treated with Choline deficiency] results in decreased expression of PPARA mRNA]; [Methionine deficiency co-treated with Choline deficiency] results in decreased expression of PPARA mRNA; Quercetin inhibits the reaction [[Methionine deficiency co-treated with Choline deficiency] results in decreased expression of PPARA mRNA] | PMID:25712622 | PPARA | multiple interactions | ISO | Ppara (Rattus norvegicus) | 6480464 | CTD | [Methionine deficiency co-treated with Choline deficiency] results in decreased expression of PPARA mRNA; geraniol inhibits the reaction [[Methionine deficiency co-treated with Choline deficiency] results in decreased expression of PPARA mRNA] | PMID:26695085 | PPARA | multiple interactions | ISO | Ppara (Mus musculus) | 6480464 | CTD | 3,4,5,3',4'-pentachlorobiphenyl promotes the reaction [[Methionine deficiency co-treated with Choline deficiency] results in decreased expression of PPARA mRNA]; [Betaine co-treated with Choline co-treated with Folic Acid co-treated with Methionine co-treated with Vitamin B 12 co-treated with Zinc Sulfate co-treated with Ethanol] results in increased expression of PPARA protein; [Methionine deficiency co-treated with Choline deficiency co-treated with 3,4,5,3',4'-pentachlorobiphenyl] results in decreased expression of PPARA mRNA; [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in decreased expression of PPARA mRNA; [Methionine deficiency co-treated with Choline deficiency] results in decreased expression of PPARA mRNA; [Methionine deficiency co-treated with Choline deficiency] results in increased expression of PPARA mRNA; alisol A 24-acetate inhibits the reaction [[Methionine deficiency co-treated with Choline deficiency] results in decreased expression of PPARA mRNA]; Chenodeoxycholic Acid inhibits the reaction [[Methionine deficiency co-treated with Choline deficiency] results in decreased expression of PPARA mRNA]; pregna-4,17-diene-3,16-dione inhibits the reaction [alisol A 24-acetate inhibits the reaction [[Methionine deficiency co-treated with Choline deficiency] results in decreased expression of PPARA mRNA]]; Quercetin inhibits the reaction [[Methionine deficiency co-treated with Choline deficiency] results in decreased expression of PPARA mRNA] | PMID:18952117 PMID:20118189 PMID:20938992 PMID:22872676 PMID:25712622 PMID:27773935 PMID:28163111 PMID:28973532 | | ||||||||||||||||||||||
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