GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | Timp1 | multiple interactions | EXP | | 6480464 | CTD | 3,4,5,3',4'-pentachlorobiphenyl promotes the reaction [[Methionine deficiency co-treated with Choline deficiency] results in increased expression of TIMP1 mRNA]; 5-(3-methoxy-5-(4-methoxystyryl)phenoxy)-2,2-dimethylpentanoic acid analog inhibits the reaction [[Methionine deficiency co-treated with Choline deficiency] results in increased expression of TIMP1 mRNA]; 5-(3-methoxy-5-(4-methoxystyryl)phenoxy)-2,2-dimethylpentanoic acid analog inhibits the reaction [[Methionine deficiency co-treated with Choline deficiency] results in increased expression of TIMP1 protein]; [3,4,5,3',4'-pentachlorobiphenyl co-treated with Methionine deficiency co-treated with Choline deficiency] results in increased expression of TIMP1 mRNA; [Choline deficiency co-treated with Folic Acid deficiency] results in increased expression of TIMP1 mRNA; [Choline deficiency co-treated with Methionine deficiency] results in increased expression of TIMP1 mRNA; [Dietary Fats co-treated with Choline deficiency] results in increased expression of TIMP1 protein; [Methionine deficiency co-treated with Choline deficiency co-treated with aroclor 1260] results in increased expression of TIMP1 mRNA; [Methionine deficiency co-treated with Choline deficiency co-treated with Dietary Fats] results in increased expression of TIMP1 mRNA; [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased expression of TIMP1 mRNA; [Methionine deficiency co-treated with Choline deficiency] results in increased expression of TIMP1 mRNA; [Methionine deficiency co-treated with Choline deficiency] results in increased expression of TIMP1 protein; alisol A 24-acetate inhibits the reaction [[Choline deficiency co-treated with Methionine deficiency] results in increased expression of TIMP1 mRNA]; alisol A 24-acetate inhibits the reaction [[Methionine deficiency co-treated with Choline deficiency] results in increased expression of TIMP1 mRNA]; Bezafibrate inhibits the reaction [[Choline deficiency co-treated with Methionine deficiency] results in increased expression of TIMP1 mRNA]; Chenodeoxycholic Acid affects the reaction [alisol A 24-acetate inhibits the reaction [[Choline deficiency co-treated with Methionine deficiency] results in increased expression of TIMP1 mRNA]]; Chenodeoxycholic Acid inhibits the reaction [[Methionine deficiency co-treated with Choline deficiency] results in increased expression of TIMP1 mRNA]; Fenofibrate inhibits the reaction [[Methionine deficiency co-treated with Choline deficiency] results in increased expression of TIMP1 mRNA]; NR0B2 protein promotes the reaction [Fenofibrate inhibits the reaction [[Methionine deficiency co-treated with Choline deficiency] results in increased expression of TIMP1 mRNA]]; PANX1 gene mutant form inhibits the reaction [[Dietary Fats co-treated with Choline deficiency] results in increased expression of TIMP1 protein]; pirinixic acid inhibits the reaction [[Methionine deficiency co-treated with Choline deficiency] results in increased expression of TIMP1 mRNA]; Quercetin inhibits the reaction [[Methionine deficiency co-treated with Choline deficiency] results in increased expression of TIMP1 mRNA]; Smoke affects the reaction [[Methionine deficiency co-treated with Choline deficiency co-treated with Dietary Fats] results in increased expression of TIMP1 mRNA] | PMID:18513333 PMID:19593819 PMID:20697377 PMID:20938992 PMID:22915297 PMID:23439872 PMID:27773935 PMID:28163111 PMID:28973532 PMID:29246445 PMID:29883724 PMID:30745416 PMID:31678261 | | ||||||||||||||||||||||
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