Send us a Message



Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   

GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 69453
Species: Homo sapiens
RGD Object: Gene
Symbol: LCN2
Name: lipocalin 2
Acc ID: CHEBI:15354
Term: choline
Definition: A choline that is the parent compound of the cholines class, consisting of ethanolamine having three methyl substituents attached to the amino function.
Chemical ID: MESH:D002794
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
LCN2multiple interactionsISOLcn2 (Mus musculus)6480464CTD[Dietary Fats co-treated with Choline deficiency] results in increased expression of LCN2 mRNA; [Methionine deficiency co-treated with Choline deficiency co-treated with Dietary Fats] promotes the reaction [cyanoginosin LR results in increased expression of LCN2 protein]; [Methionine deficiency co-treated with Choline deficiency co-treated with Dietary Fats] results in increased expression of LCN2 protein; NLRP3 protein affects the reaction [[Methionine deficiency co-treated with Choline deficiency co-treated with Dietary Fats] promotes the reaction [cyanoginosin LR results in increased expression of LCN2 protein]]; PANX1 gene mutant form inhibits the reaction [[Dietary Fats co-treated with Choline deficiency] results in increased expression of LCN2 mRNA]PMID:29246445 PMID:34416350
Go Back to source page   Continue to Ontology report