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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 2426
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Csf3
Name: colony stimulating factor 3
Acc ID: CHEBI:15354
Term: choline
Definition: A choline that is the parent compound of the cholines class, consisting of ethanolamine having three methyl substituents attached to the amino function.
Chemical ID: MESH:D002794
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
QualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
multiple interactionsISORGD:13509556480464CTD[CSF3 protein co-treated with Paclitaxel] results in decreased abundance of Choline

PMID:9018096
multiple interactionsISORGD:7314166480464CTD[Dietary Fats co-treated with Choline deficiency] results in increased expression of CSF3 protein, PANX1 gene mutant form inhibits the reaction [[Dietary Fats co-treated with Choline deficiency] results in increased expression of CSF3 protein]

PMID:29246445
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.