GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | Acaca | decreases expression | EXP | | 6480464 | CTD | Choline deficiency results in decreased expression of ACACA mRNA | PMID:25178843 | Acaca | multiple interactions | EXP | | 6480464 | CTD | [3,4,5,3',4'-pentachlorobiphenyl co-treated with Methionine deficiency co-treated with Choline deficiency] results in decreased expression of ACACA mRNA; [Methionine deficiency co-treated with Choline deficiency co-treated with Dietary Fats] results in increased expression of ACACA mRNA; [Methionine deficiency co-treated with Choline deficiency co-treated with RXRA gene mutant form] results in increased expression of ACACA mRNA; [Methionine deficiency co-treated with Choline deficiency] results in increased expression of ACACA protein; alisol A 24-acetate inhibits the reaction [[Methionine deficiency co-treated with Choline deficiency] results in increased expression of ACACA protein]; Chenodeoxycholic Acid inhibits the reaction [[Methionine deficiency co-treated with Choline deficiency] results in increased expression of ACACA protein]; pregna-4,17-diene-3,16-dione inhibits the reaction [alisol A 24-acetate inhibits the reaction [[Methionine deficiency co-treated with Choline deficiency] results in increased expression of ACACA protein]]; Smoke promotes the reaction [[Methionine deficiency co-treated with Choline deficiency co-treated with Dietary Fats] results in increased expression of ACACA mRNA] | PMID:18952117 PMID:27773935 PMID:28973532 PMID:31678261 | Acaca | multiple interactions | ISO | Acaca (Rattus norvegicus) | 6480464 | CTD | [Choline co-treated with Betaine co-treated with Vitamin B 12 co-treated with Folic Acid co-treated with Dietary Fats co-treated with Dietary Sucrose] results in increased expression of ACACA mRNA; [Folic Acid deficiency co-treated with Methionine deficiency co-treated with Choline deficiency] results in decreased expression of ACACA mRNA | PMID:19566968 PMID:22648174 | |
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