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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 736208
Species: Homo sapiens
RGD Object: Gene
Symbol: CEBPB
Name: CCAAT enhancer binding protein beta
Acc ID: CHEBI:15343
Term: acetaldehyde
Definition: The aldehyde formed from acetic acid by reduction of the carboxy group. It is the most abundant carcinogen in tobacco smoke.
Chemical ID: MESH:D000079
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
CEBPBincreases expressionISOCebpb (Mus musculus)6480464CTDAcetaldehyde results in increased expression of CEBPB proteinPMID:10613735
CEBPBmultiple interactionsISOCebpb (Mus musculus)6480464CTDAcetaldehyde promotes the reaction [CEBPB protein binds to COL1A1 enhancer]PMID:10613735
CEBPBmultiple interactionsISOCebpb (Rattus norvegicus)6480464CTD[Acetaldehyde promotes the reaction [CEBPB protein binds to COL1A1 promoter]] which results in increased expression of COL1A1 mRNA; Acetaldehyde promotes the reaction [CEBPB protein binds to COL1A1 promoter]PMID:10871045
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